The frenzy over induced pluripotent stem cells (iPS cells) in
last few years was finally topped by Monday’s Nobel Prize announcement to most disbelief,
which shows that the Nobel committee is only human and makes mistakes too. It
is the sad consequence of irresponsible research from a combination of failure
in knowledge, scientific conduct, originality, and peer review. It is the cooked
result from lack of open discussion & dialogue, transparency, open public policy
& view & opinion, open & unrestricted scientific ground, and open
mind. It is ISSCR (International Society for Stem Cell Research) and few
well-connected big names’ forced monologue cooked to appeal the political need and
interest of opponents of human embryonic stem cell (hESC) research. It is
erosion of scientific integrity and public trust. It is degraded of sciences
and Nobel Prize. It does not take a genius or a Nobel committee to tell iPS
cell is fraud. Yamanaka did not have any scientific data for the normality and
stability of iPS cells that have been used to differentiate normal stem cells
from abnormal cancer cells when it was rushed to publish in Cell, so it would come
in handy for the political climate of Bush Administration and for those against
hESC research to stall human embryonic stem cell research. Yamanaka even proved
himself that DNA integrity is damaged and DNA damage check is compromised in
iPS cells, so iPS cell is a hoax and he is irresponsible. So far, there is no
scientific evidence that iPS cells are stem cells, nor iPS cells can cure any
disease or be used for medicine, nor Yamanaka generated any cells work for any
diseases for any imminent clinical trial. Far cry from 2010 when Nobel
committee gave the IVF pioneer Robert Edwards his well–deserved Nobel Prize recognition, in 2012, Nobel committee has condescended to give Nobel Prize to the biggest
stem cell conman. See our previous posts. Also See california stem cell report and Knoepfler stem
cell blog for other opinions.
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